Anhydrotetracycline, a novel effector for tetracycline controlled gene expression systems in eukaryotic cells
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Anhydrotetracycline, a novel effector for tetracycline controlled gene expression systems in eukaryotic cells.
Tetracycline (Tc) controlled gene expression has been demonstrated in a variety of eukaryotic systems such as tobacco (1, 2, 3), Saccaromyces cerevisiae (4), Saccaromyces pombe (5) and Dictyostelium discoidum (6). In these systems the repressor of the E.coli TnlO tetracycline (Tc) resistance operon (7) is utilized to interfere with transcription initiation of RNA polymerase II or HI by binding ...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 1993
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/21.18.4411